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Simplifying the B Complex: How Vitamins B6 and B9 Modulate One Carbon Metabolism in Cancer and Beyond

DLBCL has been classified into germinal center B-cell–like (GCB) and activated B-cell–like (ABC) subtypes based on gene expression profiling [2]

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Indeed in most cellular conditions the oxidized form is only a very small fraction of the overall pool but still with physiological implications