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Some ultra-small nanoparticles designed based on this characteristic, such as ICG-PEG45 (molecular weight approximately 3 kDa) or large PEG (molecular weight 11 kDa), are exclusively excreted by the kidneys without undergoing hepatic clearance [42,89]

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(2001) tested BPC-157 on rats consuming alcohol daily for three months at 7.28 g/kg per day