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Calcium supplements , in particular, are well known to cause constipation

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Alió and his cohort say that they have observed the long-term effects of KTP after about 11 years of experimental animal and patient studies—published in places like the British Journal of Ophthalmology , the Journal of Cataract and Refractive Surgery , and Cornea —but we’re still about a decade short of the “very long-term” benchmark