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To address the larger and important point that the reviewer brings up, we explicitly analyzed dendritic spine turnover rate to allow comparison to Jiang et al 2013 and other previous studies, and indeed we found a significant increase in spine turnover rate in mutants (see new Fig

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Median baseline NIHSS was 9 (IQR 7–14) in MT versus 3 (2–6) in BMT (p 60 days post-stroke)